https://adrianzucco.com/tags/complexity/Recent content in Complexity on Adrian G. ZuccoHugo -- gohugo.ioenadrigabzu@sund.ku.dk (Adrian G. Zucco)adrigabzu@sund.ku.dk (Adrian G. Zucco)MIT License ✨ Made with ❤️ and vibes by Adrian G. ZuccoMon, 01 Sep 2025 00:00:00 +0000https://adrianzucco.com/publication/zucco-sciadv-2025/Mon, 01 Sep 2025 00:00:00 +0000adrigabzu@sund.ku.dk (Adrian G. Zucco)https://adrianzucco.com/publication/zucco-sciadv-2025/Sleep problems among young adults pose a major public health challenge. Leveraging nationwide health surveys and registers from Denmark, we investigated patterns of sleep problems from late adolescence to adulthood and explored early life-course determinants. We generated life-course embeddings using unsupervised machine learning on data from 2.2 million individuals born from 1980 to 2015. We used this landscape to identify neighboring factors of sleep problems. We observed a substantial increase in self-reported sleep problems among individuals aged 15 to 45, from 34 to 49% between 2010 and 2021, and a 10-fold increase in melatonin use. We also found relevant clusters of sleep-related prescriptions, diagnoses, and procedures with age-specific incidence patterns. Specific childhood adversities, such as sibling psychiatric illness, foster care, and parental divorce, were shared factors across multiple sleep disorders such as insomnia and nightmares. These findings underscore the complex interplay between medical and psychosocial factors in sleep.https://adrianzucco.com/project/complexity/Sat, 01 Apr 2023 00:00:00 +0000adrigabzu@sund.ku.dk (Adrian G. Zucco)https://adrianzucco.com/project/complexity/Member of the Copenhagen Health Complexity Center at the Department of Public Health, University of Copenhagen.https://adrianzucco.com/project/danlife/Wed, 01 Mar 2023 00:00:00 +0000adrigabzu@sund.ku.dk (Adrian G. Zucco)https://adrianzucco.com/project/danlife/The DANish LIFE course cohort (DANLIFE) is a nationwide, register-based, life-course cohort that is based on comprehensive and continuously updated information on social adversity and major life events from the Danish registers.https://adrianzucco.com/project/young_sleep/Wed, 01 Mar 2023 00:00:00 +0000adrigabzu@sund.ku.dk (Adrian G. Zucco)https://adrianzucco.com/project/young_sleep/Patterns, mechanisms, and dynamics underlying sleep health in young adults.