Adrian Zucco
Adrian Zucco
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Associations of functional human leucocyte antigen class I groups with HIV viral load in a heterogeneous cohort
Objective: Human leucocyte antigen (HLA) class I alleles are the main host genetic factors involved in controlling HIV-1 viral load …
Adrian G. Zucco
,
Marc Bennedbæk
,
Christina Ekenberg
,
Migle Gabrielaite
,
Preston Leung
,
Mark N. Polizzotto
,
Virginia Kan
,
Daniel D. Murray
,
Jens D. Lundgren
,
Cameron R. MacPherson
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Metabolic Profiling Early Post-Allogeneic Haematopoietic Cell Transplantation in the Context of CMV Infection
Immune dysfunction resulting from allogeneic haematopoietic stem cell transplantation (aHSCT) predisposes one to an elevated risk of …
Kirstine K. Rasmussen
,
Quenia Dos Santos
,
Cameron Ross MacPherson
,
Adrian G. Zucco
,
Lars Klingen Gjærde
,
Emma E. Ilett
,
Isabelle Lodding
,
Marie Helleberg
,
Jens D. Lundgren
,
Susanne D. Nielsen
,
Susanne Brix
,
Henrik Sengeløv
,
Daniel D. Murray
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Association between ten-eleven methylcytosine dioxygenase 2 genetic variation and viral load in people with HIV
Introduction: Identifying genetic factors that influence HIV-pathogenesis is critical for understanding disease pathways. Previous …
Daniel D. Murray
,
Birgit Grund
,
Cameron R. MacPherson
,
Christina Ekenberg
,
Adrian G. Zucco
,
Joanne Reekie
,
Lourdes Dominguez-Dominguez
,
Preston Leung
,
Dahlene Fusco
,
Julien Gras
,
Jan Gerstoft
,
Marie Helleberg
,
Álvaro H. Borges
,
Mark N. Polizzotto
,
Jens D. Lundgren
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Impact of Antibiotic Treatment on the Gut Microbiome and its Resistome in Hematopoietic Stem Cell Transplant Recipients
Antibiotic-resistant bacterial infections are increasingly an issue in allogenic hematopoietic stem cell transplant patients. How …
Jens Christian Nørgaard
,
Mette Jørgensen
,
Kasper Sommerlund Moestrup
,
Emma Elizabeth Ilett
,
Adrian G. Zucco
,
Ramtin Z Marandi
,
Marc Noguera Julian
,
Roger Paredes
,
Jens D Lundgren
,
Henrik Sengeløv
,
Cameron MacPherson
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Chest x-ray imaging score is associated with severity of COVID-19 pneumonia: the MBrixia score
Spatial resolution in existing chest x-ray (CXR)-based scoring systems for coronavirus disease 2019 (COVID-19) pneumonia is low, and …
Christian M. Jensen
,
Junia C. Costa
,
Jens C. Nørgaard
,
Adrian G. Zucco
,
Bastian Neesgaard
,
Carsten U. Niemann
,
Sisse R. Ostrowski
,
Joanne Reekie
,
Birgit Holten
,
Anna Kalhauge
,
Michael A. Matthay
,
Jens D. Lundgren
,
Marie Helleberg
,
Kasper S. Moestrup
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Early stimulated immune responses predict clinical disease severity in hospitalized COVID-19 patients
The immune pathogenesis underlying the diverse clinical course of COVID-19 is poorly understood. Currently, there is an unmet need in …
Rebecka Svanberg
,
Cameron MacPherson
,
Adrian G. Zucco
,
Rudi Agius
,
Tereza Faitova
,
Michael Asger Andersen
,
Caspar Da Cunha-Bang
,
Lars Klingen Gjærde
,
Maria Elizabeth Engel Møller
,
Patrick Terrence Brooks
,
Birgitte Lindegaard
,
Adin Sejdic
,
Anne Ortved Gang
,
Ditte Stampe Hersby
,
Christian Brieghel
,
Susanne Dam Nielsen
,
Daria Podlekareva
,
Annemette Hald
,
Jakob Thaning Bay
,
Hanne Marquart
,
Jens Lundgren
,
Anne-Mette Lebech
,
Marie Helleberg
,
Carsten Utoft Niemann
,
Sisse Rye Ostrowski
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Personalized survival probabilities for SARS-CoV-2 positive patients by explainable machine learning
Interpretable risk assessment of SARS-CoV-2 positive patients can aid clinicians to implement precision medicine. Here we trained a …
Adrian G. Zucco
,
Rudi Agius
,
Rebecka Svanberg
,
Kasper S. Moestrup
,
Ramtin Z. Marandi
,
Cameron Ross MacPherson
,
Jens Lundgren
,
Sisse R. Ostrowski & Carsten U. Niemann
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Readmissions, Postdischarge Mortality, and Sustained Recovery Among Patients Admitted to Hospital With Coronavirus Disease 2019 (COVID-19)
Many interventional in-patient coronavirus disease 2019 (COVID-19) trials assess primary outcomes through day 28 post-randomization. …
Kasper S Moestrup
,
Joanne Reekie
,
Adrian G. Zucco
,
Tomas Ø Jensen
,
Jens Ulrik S Jensen
,
Lothar Wiese
,
Sisse R Ostrowski
,
Carsten U Niemann
,
Cameron MacPherson
,
Jens Lundgren
,
Marie Helleberg
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Human Immunotypes Impose Selection on Viral Genotypes Through Viral Epitope Specificity
Understanding the genetic interplay between human hosts and infectious pathogens is crucial for how we interpret virulence factors. …
Migle Gabrielaite
,
Marc Bennedbæk
,
Adrian G. Zucco
,
Christina Ekenberg
,
Daniel D Murray
,
Virginia L Kan
,
Giota Touloumi
,
Linos Vandekerckhove
,
Dan Turner
,
James Neaton
,
H Clifford Lane
,
Sandra Safo
,
Alejandro Arenas-Pinto
,
Mark N Polizzotto
,
Huldrych F Günthard
,
Jens D Lundgren
,
Rasmus L Marvig
,
INSIGHT START Study Group
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The association of human leukocyte antigen alleles with clinical disease progression in HIV-positive cohorts with varied treatment strategies
Objectives: The Strategic Timing of AntiRetroviral Treatment (START) and Strategies for Management of Antiretroviral Therapy (SMART) …
Christina Ekenberg
,
Joanne Reekie
,
Adrian G. Zucco
,
Daniel D. Murray
,
Shweta Sharma
,
Cameron R. MacPherson
,
Abdel Babiker
,
Virginia Kan
,
H. Clifford Lane
,
James D. Neaton
,
Jens D. Lundgren
,
SMART Study Groups for the INSIGHT START
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